A curated, searchable index of the science on endogenous DMT and its relatives — from how the body builds and clears them, to receptor pharmacology, the gut–tryptamine axis, and the frontier where this chemistry meets autism. Every entry links to its source.
The idea that the human body produces its own tryptamines — and that this chemistry might run differently in autism — does not live in a single discipline. It sits at the meeting point of enzymology, receptor pharmacology, microbiome science, analytical chemistry, and clinical neuroscience. The evidence is scattered across 63 years and 151 journals.
This page gathers that evidence in one place and organizes it the way the Endogenous Psychedelic Hypothesis reads it: a signal that may begin in the gut, be shaped by how the body methylates and clears it, and end in perception at the brain's 5-HT2A receptor. Search it, filter it, and follow any entry to its source. It is meant to be the most complete open index of this literature — and it grows as the field does.